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Nicotine has a short half-life (14 hours), but cotinine can last 48 hours or more depending on metabolic factors

Additionally, packaging must contain an information message about the product, as follows: "Tobacco contains over 70 substances that cause cancer"

Chantix may cause harm to the fetus if used during pregnancy, and generally should not be used

After consulting all the scientific literature available on this subject at the time, it observed that the results of the various work had to be treated with caution, particularly because only 20 studies out of the 843 identified had followed the peer review scientific validation process